Differential accumulation of lead and zinc in double-tidemarks of articular cartilage

A. RoschgerJ.G. HofstaetterB. PemmerN. ZoegerP. WobrauschekG. FalkenbergR. SimonA. BerzlanovichH.W. ThalerP. RoschgerK. KlaushoferC. Streli Summary Introduction Long-term exposure to increased lead (Pb) concentrations is associated with several chronic diseases. The divalent cation zinc (Zn) is essential for numerous enzymes. In a recent study we found remarkably elevated concentrations of Pb and Zn in the tidemark (TM),...