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Glutathione Fine-Tunes the Innate Immune Response Toward Antiviral Pathways in a Macrophage Cell Line Independently of Its Antioxidant Properties

Marina Diotallevi, Paola Checconi, Anna Teresa Palamara, Ignacio Celestino, Lucia Coppo, Arne Holmgren, Kahina Abbas, Fabienne Peyrot, Manuela Mengozzi, and Pietro Ghezzi Glutathione (GSH), a significant cellular antioxidant, is thought to suppress the inflammatory reaction caused by reactive oxygen species (ROS) (ROS). Experiments with exogenously applied antioxidants/reducing agents or pro-oxidants, on the other hand, account...

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