GSH and Analogs in Antiviral Therapy

Alessandra Fraternale, Maria Filomena Paoletti, Anna Casabianca, Lucia Nencioni, Enrico Garaci, Anna Teresa Palamara, and Mauro Ma In animal cells, reduced glutathione (GSH) is the most common non-protein thiol. Its de novo and salvage synthesis helps to keep the cellular environment under control. GSH is the most effective intracellular antioxidant, and glutathione-S-transferases (GST) and glutathione peroxidases catalyze the detoxification of a...