Genetic detoxification of bacterial toxins: A new approach to vaccine development
Genetic detoxification of bacterial toxins: A new approach to vaccine development R Rappuoli, G Douce, G Dougan, and M Pizza For preventing a variety of different bacterial infectious diseases, toxoids or chemically detoxified bacterial toxins, have been successfully used as vaccines. Superior to the classical toxoids both in safety and in immunogenicity, genetically inactivated toxins should replace the classical...
